产品货号：
Z12544
中文名称：
BUB1抗体
英文名称：
Anti-BUB1 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-BUB1 Antibody |
| 指标别名 | BUB1;BUB1A;BUB1L;hBUB1 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse |
| 应用范围 | ELISA,WB,ICC,IF |
| 基因名称 | BUB1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | Bub1 antibody was raised against a 19 amino acid synthetic peptide from near the amino terminus of human Bub1.The immunogen is located within amino acids 40 - 90 of Bub1. |
| 计算分子量 | 122kDa |
| 成分 | Bub1 Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | Bub1 Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | Bub1 was initially identified as the mammalian homolog to the yeast protein through a cDNA screen.Bub1 encodes a kinase involved in the formation of the spindle checkpoint,an important mechanism that ensures high fidelity mitotic chromosome segregation.It is thought to be required for assembly of a functional inner centromere,sister chromatid cohesion via targeting of the Shugoshim protein and metaphase congression.Bub1 functions by phosphorylating cdc20,a member of the mitotic checkpoint complex and activating the spindle checkpoint.A related protein kinase Bub3 interacts with Bub1 and targets it to kinetochores prior to chromosome alignment.Mutations in bub1 have been associated with aneuploidy and several forms of cancer. |
| Uniprot ID | O43683 |
| 基因名全称 | Budding uninhibited by benzimidazoles 1 homolog (yeast) |
| 蛋白名全称 | Budding uninhibited by benzimidazoles 1 homolog (yeast) |
| 推荐稀释比 | Bub1 antibody can be used for detection of bub1 by Western blot at 2 ～ 4μg/mL.Antibody can also be used for immunocytochemistry starting at 10μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in mouse samples;Immunocytochemistry in mouse samples and Immunofluorescence in mouse samples.All other applications and species not yet tested. |
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